Are you dissatisfied with your inability to respond to cannabis edibles? The effects of your cannabis products depend on a variety of things.
Cannabis edibles are becoming more and more popular. Many individuals gush about how edibles make them feel. However, some folks simply don’t appear to respond to it.
In this article, we’ll look at why THC edibles don’t work for you and some alternative methods you might want to try to see if you can alter how your body reacts.
Learn the various reasons why edibles are unusually inefficient and get advice on improving your experience!
What Are Cannabis Edibles & What Do They Do?
Products containing cannabinoids that you can eat or drink are known as edible cannabis products (or edibles for short).
Cannabis edibles are snacks like candies, brownies, cookies, and other baked goods with some cannabis derivatives.
When ingested, cannabinoids — chemical elements present in cannabis — can impact your body and psyche.
Tetrahydrocannabinol, or THC, is a cannabinoid that induces euphoria and intoxication in users (usually referred to as high).
CBD (cannabidiol), a non-intoxicating cannabinoid, may offer some medicinal benefits, but further studies are needed to back this up.
Even though certain edibles resemble common foods, they’re NOT meant for regular consumption and shouldn’t be a source of nutrition.
How Do Marijuana Edibles Function?
Compared to other cannabis products, traditional edibles like weed brownies, cookies, and gummy bears affect the body differently.
Edibles must get through first-pass metabolism, absorbed through your intestines, and processed by your liver before being absorbed into the bloodstream.
Before the THC reaches your bloodstream, the body transforms it into another THC version called 11-Hydroxy-THC while in your liver.
Since 11-Hydroxy-THC is more potent and psychotropic than regular delta-9 THC, the effects of edibles sometimes have a distinctive high from other cannabis highs.
Edibles’ effects take at least 30 minutes to become noticeable, and they stay LONGER than a typical high.
However, how edibles affect you depends on more than just the THC levels you take; it also depends on how your body is structured.
Edibles Have Zero Effect on “Ediblocked” Individuals
Ediblocked people are an “unknown fraction of the population that appears to be functionally ‘immune’ to edibles, or at least has ultra-high tolerances.”
It is claimed that persons who are ediblocked can ingest amounts of cannabis that would typically cause them to enjoy a powerful high WITHOUT experiencing anything.
For those who choose to use oral intake of cannabis as medicine rather than inhalational methods, becoming ediblocked is a concern.
One may be unable to take advantage of the therapeutic and pain-relieving effects of cannabis if one cannot feel the desired effects of edibles or cannabis that has been swallowed.
The CPY2C9 gene, which codes for the enzyme that shepherds THC through its three-step metabolic transformation, is found in these people with rare subtypes.
NOTE: We’re just now beginning to understand the cannabinoid system, according to Dr. Staci Gruber, director of the McLean Hospital with Marijuana Investigations for Neuroscientific Discovery programs, who also noted that “it’s already clear that it’s not just about what and how much you’re using; it’s about how you’re wired.”
Why Cannabis Edibles Doesn’t Work for Everyone
Your tolerance for edibles is unrelated to smoking, vaping, or inhaling. Many people prefer edibles to smoking for a variety of reasons.
Factors regarding physical health are the most frequent cause. The experience is an additional factor. THC’s high in edibles can be more potent and provide a unique, all-over feeling.
Evidence shows that the intoxicating effects can linger for a few hours or longer.
Edibles are also reasonably practical because they are inconspicuous, especially around other people, and simple to eat. Unfortunately, not everyone uses them in the same way.
Numerous others claim to have experienced no effects at all. There are a few explanations for this if it applies to you. Below, we’ll go into greater detail about them:
1. Cannabis Consumption Is Insufficient
One of the main reasons cannabis edibles might not work for you is because there isn’t enough cannabis in the dosage you’re taking.
To achieve the intended effect, quite a few people need a higher dose than others. Try gradually increasing your intake if a single dose doesn’t have the desired effect.
You can also be using the wrong kind of edible, which is another problem. All edibles are not created equal. It matters what kind of cannabis is edible.
While certain cannabis strains are richer in CBD than other compounds, others are greater in cannabis. It can affect your experience and prevent you from getting the desired results.
2. The THC in Your System Is Metabolized Too Quickly
Before the active form of THC even reaches the bloodstream, it degrades into an inactive waste product.
The metabolic rate could also be a factor because THC needs to absorb and metabolize fat for the body to process it through the digestive tract.
A high metabolic rate could indicate that your body is breaking it down so quickly that you are unaware of the effects.
Before entering your bloodstream, THC is processed in your liver. The enzymes significantly influence your reaction to the cannabinoid system in your liver.
Higher or lower levels of CYP enzymes can affect the pace of cannabis metabolism and even result in the inability to metabolize cannabis properly.
3. You’re Consuming the Edible While Feeling Empty
Edibles may make some people feel something, but they may not be the outcome they hoped for. You may experience intense anxiety instead of relaxation.
Taking edibles on an empty stomach may be one of the leading causes of this.
Consuming an edible without any other food in your stomach can make the THC affect you more rapidly and create undesirable effects than if you eat beforehand.
Try eating a healthy meal and drinking lots of water before taking edibles; if you’re taking them on an empty stomach, you will experience the opposite of what you wanted.
By doing this, the absorption is slowed, preventing you from being overtaken by cannabis.
4. It Just May Not Be Right for You
Some people can’t seem to get edibles to work no matter what they try. Cannabis edibles simply don’t work, just like specific conventional medications don’t work for everyone.
Instead, you might consider experimenting with a different cannabis variety. Try a tincture if you don’t want to smoke or vape.
Many people can experience the effects of cannabinoids without smoking or vaping, but not everyone will benefit from cannabis edibles.
If the effects of your edibles aren’t what you’re looking for, ask your dispensary for advice or to suggest something different that might better fit your needs.
5. You Didn’t Decarb First
If you’ve never prepared an edible, be aware that you must first decarb your cannabis. Baking your cannabis in a conventional oven or instant pot will quickly and simply decarb it.
You probably won’t experience the benefits of your edibles if you omit this step. Remember that decarbing is required for flower buds, trim, kief, and many concentrates.
6. Not Enough Liver Enzymes
With eaten edibles, the liver functions by converting THC into the metabolite 11-OH-THC. The high is brought on by this substance, not by THC.
A compelling hypothesis is that people with an unusual variation of a key liver enzyme may be overly adept at processing ingested THC.
It converts first into an “active” metabolite that causes a high.
Enzymes carry out the process of turning THC into 11-OH-THC. Therefore, neither the conversion nor the high sensation occurs if these enzymes are lacking.
The body’s physiological variations or alterations may result in a drop in certain liver enzymes.
7. Lack of Gallbladder
Many people blame the condition on having no gallbladder; however, this is only unreliable.
We’ve heard from people who claim they feel ABSOLUTELY NOTHING because they don’t have a gallbladder compared to every person who claims they do.
The effects of edibles, however, may start more quickly or be delayed if you have your gallbladder removed.
Your body may not adequately absorb butter and other fat-based foods since the gallbladder breaks down fats and makes them usable and absorbable.
It could be preferable to try alcohol-based tinctures like the Green or Golden dragon.
8. You Have a High Tolerance
You might be perplexed why edibles used to make you feel good but no longer do. Prolonged use-related physiological changes may alter how you feel when using.
Your body builds up a tolerance to THC and other cannabinoids over time. It implies that the same effect can be achieved by just taking a more significant dose.
You might need to take a break from tolerance to counteract this.
9. Drug Interactions
Due to competition for the same liver enzymes, prescription medications can alter how cannabis is digested.
The same CYP3A4 enzyme that cannabis needs for metabolism may compete with another regularly given cholesterol-lowering drug, atorvastatin, leaving little THC.
The impact of oral cannabis (along with its potential for a psychoactive effect) may be diminished since fewer enzymes are available to create 11-OH-THC.
Anticholinergics and other prescription medications can also slow digestion, which may alter how well the food is absorbed.
Space edibles and other medications at least two hours apart to avoid potential drug interactions.
NOTE: Cannabis can be absorbed and digested by your body differently if you have certain conditions, such as gastrointestinal disorders, irritable bowel syndrome, irritable bowel disease, and other digestive issues.
Tips and Tricks to Try to Get the Desired Effects of Edibles
Are there any remedies for getting “ediblocked,” then?
Yes, and here are some possibilities to consider:
- Aim to use digestive enzymes
- Consider taking it with food or fat
- Try pairing it with mango
- Switch to alternate strategies
The body’s inability to create enough liver enzymes may be compensated for by taking digestive enzyme supplements.
Anecdotal evidence suggests that consuming edibles and enzymes can help you quickly feel high and prolong it.
Digestive enzymes are sold over-the-counter (OTC) at your neighborhood pharmacy or online, but before attempting anything new, consult your doctor.
Eat Edibles With a Meal or Fat
Some people discover that ingesting edibles on an empty stomach has little to no impact, whereas consuming edibles with a meal has a far more positive outcome.
Because they are lipophilic, cannabinoids are drawn to fat. The bioavailability, or how readily your body can use it, is IMPROVED when combined with fat.
Additionally, when you eat a meal, your digestive system usually functions and creates the necessary enzymes to break down the food.
It can assist in starting the enzyme process that breaks down THC into 11-OH-THC.
Pair With Mango
According to anecdotal evidence, eating mangoes with edibles can significantly benefit some people. Myrcene, a terpene found in mangoes, can improve your cannabis journey.
According to the Entourage Effect, the psychoactive component of THC interacts with the terpenes in mangoes to increase your high.
In addition to eating fresh mangoes, you can prepare foods with mango as a critical ingredient.
Try Different Methods
It may be time to switch to alternative consumption methods if you discover that edibles do not suit your needs after considerable patience and experimentation.
One of the five most popular cannabis application methods is edibles. Then, you may try:
- When applied under the tongue, sublingual cannabis can enter the bloodstream.
- Inhalation is not limited to smoking; you can also try dry herb vaping.
- Apply your preferred cannabis topical medicines directly to the skin for targeted relief.
- Cannabis can enter the bloodstream when used as a suppository, which is inserted into the body.
Cannabis Edibles Alternatives
There are PLENTY of other fantastic cannabis options, so don’t be disappointed!
Why don’t edibles work for me? Finding the cannabis consumption strategy that works best for you may require some experimentation, but that’s fun.
Of course, the most common choices are flowers and concentrate.
However, there are a few cannabis product alternatives for patients who prefer to use cannabis products that are similar to edibles, such as the following:
1. Tinctures and Sprays
Sublingual, or under-the-tongue, products like tinctures and sprays transfer THC straight into the bloodstream via the mucous membrane beneath the tongue.
An ordinary cannabis oil tincture or spray comes in a tiny vial with a dropper or spray tip. Allow the product to absorb while holding it under your tongue.
2. Sublingual Mints, Suckers, and Other Candies
A more delectable sublingual choice is comparable to an edible one, but the body absorbs the cannabinoids through the soft mouth tissue rather than through your stomach.
The effects of a sublingual tincture or mints wear off MORE QUICKLY than conventional edibles and take roughly 15 minutes to begin working.
3. Transdermal Patches and Topicals
When a cannabis product for the skin is referred to as “transdermal,” it signifies that the THC it contains can cause psychoactive effects since it enters your body through your skin.
Non-transdermal patches and topicals reduce pain and inflammation without making you euphoric. For precise pain treatment, topicals and patches are ideal.
As they melt, cannabis suppositories that you can inject into your vagina or anus deliver THC into the delicate tissue in your body.
A WELL-KNOWN and HIGHLY EFFICIENT delivery method for cannabis therapy is suppositories.
What Are the Different Types of Cannabis Edibles?
State by state, the sorts of edibles available at dispensaries in your area may vary, but this list includes several tried-and-true favorites:
1. Baked Goods
You’ve probably heard of marijuana brownies, a type of baked good. Some of the most common cannabis edible products are baked foods.
In addition, the market for baked cannabis goods has rapidly grown. You can now purchase cookies, pancakes, brownies, muffins, and more, depending on state laws.
2. Gummies and Chews
Various sizes and forms are available for these sweet, chewy products.
Even though edibles have a candy-like appearance and flavor, it’s vital to keep in mind that dosages vary, and you should be cautious when choosing your dosage to prevent unpleasant side effects.
3. Hard Candies and Mints
These edibles are made precisely like regular candies, but they have THC distillate injected into them.
Most marijuana edibles that resemble hard candies are made to be ingested through the tongue or cheek wall. This may have a rapid onset effect compared to less potent oral sweets.
There may be a bar of cannabis chocolate out there for you if you enjoy a certain kind of chocolate, such as white chocolate, dark chocolate, mint chocolate, or cookies and cream.
Candy lovers now have a way to enjoy their favorite dessert while also getting high, thanks to chocolate-infused cannabis edibles.
5. Drinks and Drink Mixes
Cannabis-infused beverages are becoming more and more well-liked among marijuana users. Anything from seltzers to juices, teas, and other drinks is available.
Additionally, drink mixes can assist you in brewing the ideal beverage at home if you choose to make your drinks.
6. Baking and Cooking Oils
Look into baking and cooking oils infused with cannabis to make your edibles home.
You may add cannabis to your (adults only!) meals with various items, including cannabutter and taco seasoning.
7. Savory Snacks
Not everyone likes sugary snacks. Some of us favor savory, salty nibbles that make us feel high. Tasty snack foods might be the BEST CHOICE if this describes you.
These are available in several flavors, including peanut butter, cheesy biscuits, and doughy pretzels.
Frequently Asked Questions (FAQs)
Below are the answers to the most often asked questions about cannabis edibles not working for everyone:
Is It Possible That Edibles Don’t Work for Me?
Yes. After consuming an edible, some people could have a delayed reaction. The effects of the consumable may not be felt at all at first, but they may hit hard and quickly.
Can You Build a Tolerance for Edibles?
It influences the brain’s cannabinoid type 1 (CB1) receptors. THC consumption frequently causes a gradual decline in CB1 receptor density.
It implies that a given amount of cannabis won’t have the same effect on CB1 receptors, leading to diminished results. The process by which tolerance grows is not strictly regulated.
Do Cannabis Edibles Affect Your Liver?
While experiencing digestive discomfort while consuming cannabis edibles is possible, the likelihood of suffering from acute health hazards such as liver damage is HIGHLY REMOTE.
How Long Do Edibles Take to Reach a Full Stomach?
Patience is crucial when using edibles.
Typically, it takes roughly an hour to experience effects when cannabis is ingested on an empty stomach — or up to 3 hours when edibles are eaten combined with meals.
Do Edibles Require a Certain Strain?
There are no strain-specific effects, but they will make you very high at the right dosage.
The special effects you experience are more a result of the production process than the particular cannabis variety employed in the formulation.
Conclusion: Take Care and Consider Your Options
Be careful while trying different cannabis if you’re a member of the “edibles don’t work on me” crowd and believe you might simply have a very high THC tolerance.
A specific amount of cannabis may not impact you in an edible, but that DOESN’T GUARANTEE that the same amount taken as an under-the-tongue tincture won’t.
And if you only want to use cannabis for its therapeutic properties and don’t want to get high, seek total- or broad-spectrum CBD products.
For best medicinal efficacy, these medicines must contain chemicals from the entire cannabis plant, but they don’t have any psychoactive effects.
Why, then, do edibles not work for me? The average edible just doesn’t seem to work for some people. Because of their body size and tolerance, each person’s high is different in intensity.
Patients may feel a little helpless as a result, but there are a lot of alternatives that are ideal for you. Diet, physical activity, and exercise might help to boost your metabolism.
Try exploring different cannabis options if you’ve decided that edibles don’t work for you.
Although edibles can be incredible, not everyone will enjoy them. It may not work for some for various reasons, and at least one barrier prevents edibles from getting you high.
Like other forms of cannabis intake methods, edibles have advantages and disadvantages. Some consumers will respond better to edibles than others.
The optimal way to consume cannabis for you will depend on your personal preferences and needs, whether or not you encounter the difficulties listed above, and other factors.
Even yet, we would argue that before giving up on the world of edibles totally, it is worthwhile to try with diet, physical activity, and other metabolism-boosting body hacks.
We hope this advice helps you understand why this might be happening and offers you some fresh ideas for how to improve your experience.
Happy chomping, and good luck with your upcoming edibles session!